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The Top Benefits of Bile Salts

author avatar Dr. Eric Berg 03/08/2024

The benefits of bile salts are often overlooked, despite their essential role in maintaining optimal health. Bile is produced in the liver and is crucial in digestion, nutrient absorption, and detoxification.

Discover the various advantages of bile salts, like preventing gallstones and improving nutrient absorption. Additionally, they aid in balancing gut health and supporting thyroid function - both critical aspects of maintaining good health.

Understanding Bile Salts Benefits

Bile salts are essential for the digestion of fats and are needed to absorb fat-soluble vitamins (A, E, D, and K) from food.

They also play a crucial role in maintaining gut health and facilitating detoxification. This article will explore nine benefits of taking purified bile salts on an empty stomach and how ox bile supplements can benefit your digestive health.

The Importance of Bile Salts in Digestion

Bile is a fluid produced by the liver and stored in the gallbladder. Bile salts are essential for breaking down dietary fats into smaller particles our bodies can absorb.  Bile salts, the primary components of bile, emulsify large fat globules into tiny droplets easily digested by lipase enzymes.

  • Fat digestion: Bile salts help break down ingested fats so they can be absorbed through the intestinal wall.

  • Vitamin absorption: By aiding in fat breakdown, bile salts enable better absorption of essential fat-soluble nutrients, such as vitamins A, D, E, and K.

  • Gut health maintenance: Healthy bile salt levels contribute to optimal gut function and prevent digestive issues such as constipation or diarrhea.

Bile salts have several other benefits when ingested in a fasted state, such as lowering the risk of gallstones, improving thyroid function, enhancing thyroid performance, and minimizing inflammation. 

Preventing Gallstones with Bile Salts

Bile salts are essential for a healthy gallbladder and may prevent the development of gallstones. Natural bile salts can be supplemented to maintain normal bile flow.

Impaired bile flow can cause gallbladder sludge and the formation of small deposits that can develop into gallbladder stones. These small, pebble-like deposits can cause severe pain and complications if left untreated.

Let's explore how bile salt supplementation aids in gallstone prevention.

How Bile Salt Supplementation Aids in Gallstone Prevention

Gallstones are formed when cholesterol, bilirubin, or other substances found in bile crystallize and accumulate within the gallbladder. One significant benefit of taking purified bile salts on an empty stomach is their ability to decrease the risk of gallstone formation by:

  • Dissolving existing cholesterol crystals: Bile salts help break down cholesterol crystals into smaller particles that can be easily eliminated from your body.

  • Maintaining optimal bile flow: Adequate levels of bile ensure proper digestion and absorption while reducing the chances for crystal buildup.

  • Inhibiting further cholesterol crystal growth: Bile salts prevent it from forming new stones by dissolving excess cholesterol.

Taking purified bile salt supplements regularly helps maintain optimal gallbladder function and prevents potential gallstone complications, such as inflammation, infection, or blockage within your biliary system.

If you are experiencing symptoms like abdominal pain after eating fatty meals or have been diagnosed with sluggish gallbladder or gallbladder sludge, consider a high-quality bile salt supplement to improve digestion and support the health of your intestinal tract.

Improving Nutrient Absorption

Bile salts enhance the body's ability to extract essential nutrients from dietary sources.

Bile salts are essential for absorbing fat-soluble vitamins and omega-3 fatty acids, which are crucial for a healthy body. Let's delve deeper into their roles in extracting these valuable nutrients.

Role in Extracting Fat-Soluble Vitamins

Vitamins A, E, D, and K are essential for the body's functioning, from vision to immune system health, antioxidant protection of cells, and regulating calcium levels in bones and blood clotting processes.

For instance, vitamin A is necessary for healthy vision and immune function; vitamin E acts as an antioxidant protecting cells from free radical damage; vitamin D helps maintain strong bones by regulating calcium levels; and vitamin K aids blood clotting and bone metabolism.

Bile salts emulsify fats in our food by breaking them into smaller droplets that the intestines can easily absorb. This process increases the surface area for enzyme activity, ensuring proper extraction of dietary fats and fat-soluble vitamins during digestion.

Importance of Absorbing Omega-3 Fatty Acids

Omega-3 fatty acids, such as EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), are essential for maintaining a healthy heart and brain function and have been found to have potent anti-inflammatory properties.

The body can’t produce fatty acids, and omega-3 fats must be obtained through dietary sources or supplementation.

Like fat-soluble vitamins, omega-3 fatty acids require bile salts for efficient absorption. Bile salts ensure the body can digest and absorb these lipids by emulsifying dietary fats containing these vital nutrients. 

Taking a purified bile salt supplement daily on an empty stomach can increase the absorption of fat-soluble vitamins and omega-3 fatty acids, promoting health. This can ultimately contribute to overall well-being while supporting various bodily functions.

Gut bacteria, gut flora, microbiome. Bacteria inside the small intestine

Balancing Gut Health

Maintaining appropriate levels of bile can alleviate constipation or diarrhea caused by microbial imbalances in the intestines while supporting liver health.

This makes bile salts effective in lowering the risk of various diseases, such as hepatitis infections linked to liver disease and cirrhosis. This section will discuss how bile salts help alleviate constipation through lubrication and reducing small intestinal bacterial overgrowth (SIBO).

Alleviating Constipation Through Lubrication

Constipation is a common issue faced by many individuals worldwide. One of the primary reasons for constipation is insufficient bile production or flow. Bile salts are crucial in maintaining gut health by acting as natural laxatives that promote bowel movements.

Taking purified bile salts helps to lubricate the intestines and soften stool consistency, making it easier for waste materials to pass through smoothly.

Reducing Small Intestinal Bacterial Overgrowth (SIBO)

Small intestinal bacterial overgrowth (SIBO) occurs when excessive growth of potentially harmful microbes in the small intestine. This condition can lead to symptoms like bloating, abdominal pain, gas formation, and malabsorption issues.

  • Antimicrobial properties: Bile salts possess antimicrobial properties that can inhibit harmful bacteria's growth, thus preventing SIBO. They help maintain a healthy balance of gut bacteria by selectively targeting pathogenic strains without affecting beneficial ones.

  • Enhancing intestinal motility: Bile salts also promote intestinal motility, essential for maintaining proper digestion and preventing bacterial overgrowth. Bile salts stimulate the contraction of gut muscles, transporting food and waste products through your digestive tract. 

Incorporating purified bile salts into your daily routine may help to improve gut health and prevent common gastrointestinal issues such as constipation and SIBO. However, consulting a healthcare professional before starting any new supplement regimen is crucial. 

Supporting Thyroid Function

The conversion of thyroid hormones (T4) into their active form (T3) requires adequate bile salts. Research has shown that insufficient bile salt levels can lead to poor hormone conversion, resulting in hypothyroidism symptoms.

Bile Salts Role in Thyroid Hormone Conversion

Bile salts are released into the small intestine during digestion and are essential for breaking down fats and aiding nutrient absorption.

In addition, bile salts also facilitate thyroid hormone activation, specifically converting inactive T4 hormones into active T3 hormones - this is vital for regulating metabolic pathways and energy production.

Benefits of Bile Salts for Hypothyroidism

  • Improved energy levels: Proper thyroid hormone conversion plays a significant role in energy production; therefore, ensuring sufficient bile salt levels may help alleviate fatigue, a primary symptom of hypothyroidism. 

  • Maintaining a healthy weight: Since an underactive thyroid can slow the metabolism and cause weight gain and difficulty losing, supplementing with purified bile salts on an empty stomach might support healthy weight management in individuals with hypothyroidism.

  • Reduced hair loss: Adequate thyroid hormone levels are essential for hair growth and maintenance. By supporting the conversion of T4 to T3, bile salts may help reduce the hair loss commonly associated with hypothyroidism.

Incorporating purified bile salts into your daily routine may potentially assist those suffering from hypothyroidism symptoms. It is essential to consult with a healthcare professional before starting any supplementation regimen, especially if you have pre-existing medical conditions or are currently taking medications that might interact with bile salt supplements.

Supporting Healthy Inflammatory Responses & Reducing Pain

Bile salts can support healthy inflammatory responses and assist with associated pain, making them potentially beneficial for those with autoimmune diseases.

Moreover, bile salts can alleviate pain associated with gallbladder congestion or nerve irritation by thinning sludge buildup and promoting normal gallbladder function.

The Potential Anti-Inflammatory Properties of Bile Salts

Bile salts have been shown to support some anti-inflammatory properties. Bile salts help activate vitamin D receptors in the body, which assists in regulating the body's immune system and inflammatory response, thus supporting the health in various tissues, including joints, skin, and digestive organs.

For individuals suffering from chronic autoimmune conditions like rheumatoid arthritis or psoriasis, supplementing with bile salts may support the relief of inflammatory responses and ease symptoms.

Alleviating Right Shoulder Pain Caused by Gallbladder Issues

Bile salts may help relieve localized discomfort caused by gallbladder problems such as congestion or nerve irritation.

Insufficient bile production, or bile that has become too thick, can lead to impaired gallbladder function resulting in symptoms like right shoulder pain - commonly referred to as "gallbladder referral pain."

By supplementing with bile salts, individuals can promote the thinning of bile and support normal gallbladder function. This process helps to alleviate pain by reducing pressure on surrounding nerves and tissues.

Studies have demonstrated that regular intake of purified bile salts can significantly reduce symptoms associated with gallbladder dysfunction, including right shoulder pain.


Bile salts are essential for digestion, helping to break down and absorb fats, boost nutrient uptake, maintain intestinal health, promote thyroid function, and reduce discomfort and inflammation.

Bile salt supplements, such as ox bile, can also aid in preventing cholesterol gallstones and bile acid deficiency.


1. What are the Benefits of Taking Bile Salts?

Bile salts may offer several potential health benefits, including preventing gallstones, improving nutrient absorption (particularly fat-soluble vitamins and omega-3 fatty acids), supporting gut health by reducing small intestinal bacterial overgrowth (SIBO), and alleviating constipation.

They also support thyroid function, and can help alleviate pain related to gallbladder issues.

2. Can You Take Bile Salts Every Day?

You can take bile salts daily to support digestion and overall health. However, following the recommended dosage on the product label or consulting with a healthcare professional before starting any supplementation regimen is essential.

3. What are the Disadvantages of Taking Bile Salts?

Potential disadvantages of taking bile salts include diarrhea or loose stools due to increased water content in the intestines.

Additionally, long-term use may lead to imbalances in gut bacteria or interfere with certain medications, and it’s essential to consult your healthcare provider before starting any new supplement regimen.


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