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What Does Vitamin D3 Have To Do With MS Remission?

author avatar Dr. Eric Berg 04/17/2024

While most people know vitamin D to be an important nutrient, not many people understand the full range of benefits it can provide. This is especially true when it comes to dealing with multiple sclerosis.

Learn about how vitamin D can help manage multiple sclerosis and what steps you can take to increase your intake of this nutrient.

The Connection Between Sun Exposure and MS Incidence

Ever wondered why multiple sclerosis (MS) rates are lower near the equator? It's because the sunnier weather means more exposure to sunlight, our body's primary source of vitamin D.

Research shows a strong link between low levels of sun exposure, leading to reduced vitamin D synthesis in the skin, and higher incidence rates of MS. This correlation implies an essential role for vitamin D in combating this debilitating disease.

In short, ample sunshine helps us produce more Vitamin D3, which may be crucial in controlling certain autoimmune conditions.

Vitamin D is not merely a vitamin but rather acts like a hormone affecting over 3K genes in the body.

Vitamin D written in the sand

The Influence of Vitamin D on Genetic Expression and Bodily Functions

Vitamin D is integral to many bodily functions, including bone health and immune response. This is due to its ability to modulate gene expression via Vitamin D Receptors (VDRs).

Vitamin D Receptor Mutations and Their Impact on Absorption

Sometimes, though, mutations can occur in these VDRs, which may affect how well we absorb this vital nutrient.

These mutations or alterations have been linked with several diseases, including multiple sclerosis.

Understanding our genetics helps us understand why some people need more sunshine or supplements than others.

The Relationship Between Vitamin D Levels and Parathyroid Hormone

Vitamin D levels have a direct impact on parathyroid hormone (PTH). The PTH is vital for regulating calcium metabolism in the body. When vitamin D levels are low, it leads to an increase in PTH production.

This spike can result in too much calcium being pulled from our bones, weakening them over time. But when we boost our vitamin D3 intake, we can keep PTH under control.

Vitamin D helps maintain proper calcium and phosphorus levels in the blood, which are essential for strong bones.

The Role of Vitamin K2 in Preventing Calcium Accumulation

To add another layer of protection against excessive calcification, supplementing with vitamin K2 can be beneficial while taking high doses of vitamin D3.

Where vitamin D increases calcium absorption into the bloodstream, K2 directs it toward bones and teeth instead of letting it settle elsewhere.

Importance of Supplementing Vitamin D3 with Other Nutrients

Taking high doses of vitamin D3 can offer potential benefits for autoimmune conditions like MS. Combining this nutrient with others is essential to maximize the advantages of your supplement program.

The Role of Vitamin K2 in Preventing Calcium Accumulation

Vitamin K2 is one such ally. This particular version - MK7 - helps prevent calcium accumulation that might occur when taking large amounts of vitamin D3.

It directs calcium into our bones and teeth where we need it, rather than letting it settle in places we don't want it – like our arteries or kidneys.

Adding vitamin K supplements may boost the effectiveness of your daily dose of vitamin D).

Omega-3s: Another Crucial Co-star.

You've likely heard about omega-3 fatty acids being good for heart health, but did you know these guys also help optimize your body's use of vitamin D? They promote anti-inflammatory responses, which are often damaged by autoimmune diseases.

High doses of vitamin D3 can increase calcium concentration in your body, so hydration is key.

Research shows that taking high doses of vitamin D3 without proper hydration may raise risks for kidney stone formation. Drinking sufficient water helps dilute the excess calcium in your urine. The more diluted it is, the less likely you are to develop these painful stones.

Vitamin D3 illustration

Vitamin D3 Dosage for Multiple Sclerosis

Vitamin D3 has gained attention for its potential benefits in managing multiple sclerosis (MS). Research suggests that maintaining adequate vitamin D levels may play a role in reducing the risk of MS relapses and supporting overall neurological health.

Many healthcare professionals recommend a daily dosage of vitamin D3, such as 5000 IU, to ensure individuals with MS receive its potential benefits.

These higher dosages can help bolster vitamin D levels, contributing to better managing MS symptoms and improving overall well-being.

To fully understand the vitamin D3 benefits for multiple sclerosis, it's crucial to consult with a healthcare provider who can tailor recommendations to your specific needs and condition.


Vitamin D's significance extends beyond its traditional role as a nutrient, particularly in managing multiple sclerosis (MS). Understanding its impact on immune function and genetic expression is crucial.

By optimizing vitamin D intake, individuals may reduce MS relapses and support neurological health.

Supplementing with vitamin K2 and omega-3 fatty acids enhances its effectiveness. However, careful dosing and hydration are necessary to avoid adverse effects.

Consulting healthcare professionals for personalized guidance is key to maximizing the benefits of vitamin D in MS management and overall well-being.

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