Use apple cider vinegar for muscle cramps. There are many home remedies for muscle cramps, but apple cider vinegar is one of the most effective. The acetic acid in apple cider vinegar can help to relieve muscle cramps by helping to break down the lactic acid that builds up in muscles during exercise. Simply mix 1 tablespoon of apple cider vinegar with 8 ounces of water and drink before or after exercise. You can also massage the mixture into your muscles to help relieve cramping.